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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8
All Species:
18.79
Human Site:
Y396
Identified Species:
51.67
UniProt:
Q12929
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12929
NP_004438.3
822
91882
Y396
D
T
I
D
F
L
N
Y
T
V
N
G
D
E
R
Chimpanzee
Pan troglodytes
XP_528750
1001
111581
P587
L
A
S
S
V
L
S
P
L
L
N
K
D
T
I
Rhesus Macaque
Macaca mulatta
XP_001091077
1055
116825
Y621
D
T
I
D
F
L
N
Y
T
V
N
G
D
E
R
Dog
Lupus familis
XP_534881
791
88639
Y366
D
T
I
D
F
L
N
Y
T
V
N
N
D
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q08509
821
91720
Y396
D
T
V
D
F
L
N
Y
T
A
T
A
E
E
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416405
831
92642
Y399
D
T
I
D
F
L
Q
Y
T
V
T
S
E
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956536
804
88650
T383
E
A
I
E
F
L
H
T
A
G
S
A
E
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392229
880
100126
N361
L
L
T
R
E
A
V
N
L
L
I
N
C
V
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785396
970
107261
N536
Q
A
V
D
L
L
Q
N
C
L
T
S
R
Q
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.7
76.1
91.1
N.A.
88.9
N.A.
N.A.
N.A.
79.7
N.A.
51.8
N.A.
N.A.
28.8
N.A.
25.5
Protein Similarity:
100
79
77.1
93.4
N.A.
94.8
N.A.
N.A.
N.A.
88.5
N.A.
66.9
N.A.
N.A.
47.2
N.A.
42.3
P-Site Identity:
100
20
100
93.3
N.A.
66.6
N.A.
N.A.
N.A.
66.6
N.A.
33.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
33.3
100
93.3
N.A.
80
N.A.
N.A.
N.A.
73.3
N.A.
66.6
N.A.
N.A.
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
12
0
0
12
12
0
23
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% C
% Asp:
56
0
0
67
0
0
0
0
0
0
0
0
45
0
0
% D
% Glu:
12
0
0
12
12
0
0
0
0
0
0
0
34
67
0
% E
% Phe:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
23
0
0
12
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
56
0
0
0
0
0
0
0
12
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% K
% Leu:
23
12
0
0
12
89
0
0
23
34
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
45
23
0
0
45
23
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
23
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
56
% R
% Ser:
0
0
12
12
0
0
12
0
0
0
12
23
0
0
0
% S
% Thr:
0
56
12
0
0
0
0
12
56
0
34
0
0
12
12
% T
% Val:
0
0
23
0
12
0
12
0
0
45
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _